Phone:

(317) 278-0370

Email:

jialhan@iu.edu

Campus:

IU Fort Wayne

Resume/CV

Biography

Jiali Han, PhD, is currently professor and chair, Department of Epidemiology, Richard M. Fairbanks School of Public Health, and Rachel Cecile Efroymson professor of cancer research at Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis. Dr. Han earned his PhD in Biological Sciences in Public Health from Harvard University in 2004. He then joined the faculties of Harvard Medical School and the Harvard School of Public Health. Prior to his move to Indianapolis in 2013, he was an associate professor of epidemiology at Harvard School of Public Health, and associate professor of medicine and dermatology at Brigham and Women’s Hospital and Harvard Medical School.

Dr. Han has been the principal investigator on a dozen of NIH grants. He also serves as a key investigator on multiple NIH-funded projects, providing critical expertise in genetic and molecular epidemiology to his collaborators and peers. He has published over 240 original research articles in peer-reviewed journals. A series of his seminal research findings has been published in high-profile journals and drew enormous attention not only from the scientific community but also from public media. Dr. Han has been invited to speak about his research at regional, national, and international scientific meetings. He has served as ad hoc reviewer for over 100 peer-reviewed scientific journals.

Dr. Han has served on a number of national and international committees and grant review panels in the NIH study sections, the U.S. Department of Defense, and the American Cancer Society. He has been on several committees and chaired sessions of national and international scientific societies.

Dr. Han has shown tremendous dedication to training and mentorship. He has mentored and co-mentored over 40 graduate students, medical students, fellows, clinicians, and junior faculty members. Many of them have gone on to academic and research careers globally.

Research Interests

Dr. Han initiated his research journey in exploring the genetic and molecular epidemiology of cancer, delving into its etiology, prevention, and outcomes. His comprehensive research spans across diverse domains of human health, integrating basic science, clinical medicine, data science, informatics, technology, and community.

Internationally, he spearheads consortia investigating genetic susceptibility to keratinocyte carcinoma. Taking charge post-"genome-wide association study," Dr. Han collaborates on efforts for the integrative and functional analysis of genetic variants linked to skin cancer. His expertise extends to studying cancer screening strategies on a global scale, with a keen focus on global health settings. With significant experience in pharmaco-epidemiology and real-world evidence research, Dr. Han collaborates extensively with pharmaceutical companies.

A unique facet of his research involves exploring opioid response-mediated addictive behaviors among tanning bed users. Recently, he has delved into sports and exercise epidemiology and examined community-built environments for wellbeing.

Global Health

Dr. Han exhibits a passionate commitment to global health research and education. Actively contributing to the strategic planning and implementation of global health initiatives at the Fairbanks School of Public Health at Indiana University Indianapolis, he has amassed a track record in this field. His global health engagements include teaching a graduate-level course in Bangkok, Thailand, and serving as the Principal Investigator for an International Development Fund grant in the past.

Dr. Han had several peer-reviewed publications studying breast cancer screening strategies in developing countries, and he has numerous peer-reviewed publications from diverse international collaborations.

In 2023, he conducted a workshop in Kenya and delivered a keynote speech at the 6th Africa International Biotechnology and Biomedical Conference. Currently, Dr. Han is involved in the planning stages of developing cancer prevention and control programs in collaboration with NCI-Kenya, while also contributing to the design of new public health programs globally.

Selected Publications (over 250 original articles)

• Han J, Kraft P, Nan H, Guo Q, Chen C, Qureshi A, Hankinson SE, Hu FB, Duffy DL, Zhao ZZ, Martin NG, Montgomery GW, Hayward NK, Thomas G, Hoover RN, Chanock S, Hunter DJ. A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation. PloS Genetics. 2008 May 16;4(5):e1000074.
• Schernhammer ES, Razavi P, Li TY, Qureshi AA, Han J. Rotating night shifts and risk of skin cancer in the Nurses’ Health Study. J Natl Cancer Inst. 2011 Apr 6; 103(7): 602-6.
• Nan H, Du M, De Vivo I, Manson JE, Liu S, McTiernan A, Curb JD, Lessin L, Bonner MR, Guo Q, Qureshi AA, Hunter DJ, Han J. Shorter telomeres associate with a reduced risk of melanoma development. Cancer Res. 2011;71:6758-63.
• Zhang M, Qureshi AA, Geller AC, Frazier L, Hunter DJ, Han J. Use of tanning beds and incidence of skin cancer. J Clin Oncol. 2012 May 10;30(14):1588-93. An invited editorial accompanying the article (1571-73).
• Song F, Qureshi AA, Han J. Increased caffeine intake is associated with reduced risk of basal cell carcinoma of the skin. Cancer Res. 2012 Jul 1;72(13):3282-9.
• Shoag J, Haq R, Zhang M, Liu L, Rowe GC, Jiang A, Koulisis N, Farrel C, Amos CI, Wei Q, Lee JE, Zhang J, Kupper TS, Qureshi AA, Cui R, Han J*, Fisher DE*, Arany Z* (*co-senior authors). PGC-1 coactivators regulate MITF and the tanning response. Mol Cell. 2013 Jan 10;49(1):145-57.
• Song F, Qureshi AA, Giovannucci E, Fuchs C, Chen W, Stampfer MJ, Han J. Non-melanoma skin cancer and risk of second primary cancer. PLoS Med. 2013;10(4):e1001433.
• Bao Y, Han J, Hu FB, Giovannucci EL, Stampfer MJ, Willett WC, Fuchs CS. Association of nut consumption with total and cause-specific mortality. N Engl J Med. 2013 Nov 21; 369 (21): 2001-11.
• Li W, Qureshi AA, Ma J, Goldstein AM, Giovannucci E, Stampfer MJ, Han J. Personal history of prostate cancer and increased risk of incident melanoma in the United States. J Clin Oncol. 2013 Dec 10;31(35):4394-9. PMID: 24190118. Editorial on ASCO Post. Mar 15, 2014, Volume 5, Issue 5, Melanoma and Prostate Cancer: Two Sides of One Coin?
• Li W, Qureshi AA, Robinson K, Han J. Sildenafil use and increased risk of incident melanoma in US men: a prospective cohort study. JAMA Intern Med. 2014 Jun;174(6):964-70. An invited editorial accompanied the article (970-1). PMID: 24710960 An invited editorial accompanied the article. 2014 Jun;174(6):970-1.
• Zhang M, Zhang X, Qureshi AA, Eliassen AH, Hankinson SE, Han J. Association between cutaneous nevi and breast cancer in the Nurses’ Health Study: a prospective cohort. PLoS Med. 2014 Jun 10;11(6):e1001659. An invited editorial accompanied the article (e1001661).
• Wu S, Han J, Feskanich D, Cho E, Stampfer MJ, Willett WC, Qureshi AA. Citrus Consumption and Risk of Cutaneous Malignant Melanoma. J Clin Oncol. 2015 2015 Aug 10;33(23):2500-8. An invited editorial accompanied the article. 2015 Aug 10;33(23):2487-8.
• Chahal H, Lin Y, Ransohoff K, Hinds DA, Wu W, Dai HJ, Qureshi AA, Li WQ, Kraft P, Tang JY, Han J*, Sarin KY* (*co-senior and co-corresponding authors). Genome-wide association study identifies novel susceptibility loci for cutaneous squamous cell carcinoma. Nat Commun. 2016 Jul 18;7:12048. doi: 10.1038/ncomms12048.
• Chahal H, Wu W, Ransohoff K, Yang L, Hedlin H, Desai M, Lin Y, Dai HJ, Qureshi AA, Li WQ, Kraft P, Hinds DA, Tang JY, Han J*, Sarin KY* (*co-senior and co-corresponding authors). Genome Wide Association Study Identifies 14 Novel Risk Alleles Associated with Basal Cell Carcinoma. Nat Commun. 2016 Aug 19;7:12510. doi: 10.1038/ncomms12510.
• Duffy DL, Zhu G, Li X, Sanna M, Iles MM, Jacobs LC, Evans DM, Yazar S, Beesley J, Law MH, Kraft P, Visconti A, Taylor JC, Lui F, Wright MJ, Henders AK, Bowdler L, Glass D, Ikram AM, Uitterlinden AG, Madden PA, Heath AC, Nelson EC, Green AC, Chanock S, Barrett JH, Brown MA, Hayward NK, MacGregor S, Sturm RA, Hewitt AW; Melanoma GWAS Consortium, Kayser M, Hunter DJ, Newton Bishop JA, Spector TD, Montgomery GW, Mackey DA, Smith GD, Nijsten TE, Bishop DT, Bataille V, Falchi M, Han J*, Martin NG* (*co-senior authors). Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. Nat Commun. 2018 Nov 14;9(1):4774. doi: 10.1038/s41467-018-06649-5.
• Sarin KY*, Lin Y, Daneshjou R, Ziyatdinov A, Thorleifsson G, Rubin A, Pardo LM, Wu W, Khavari PA, Uitterlinden A, Nijsten T, Toland AE, Olafsson JH, Sigurgeirsson B, Thorisdottir K, Jorgensen E, Whittemore AS, Kraft P, Stacey SN, Stefansson K, Asgari MM, Han J* (co-corresponding authors). Genome-wide meta-analysis identifies eight new susceptibility loci for cutaneous squamous cell carcinoma. Nat Commun. 2020 Feb 10;11(1):820. doi: 10.1038/s41467-020-14594-5.
• Zhang Y, Birmann BM, Han J, Giovannucci EL, Speizer FE, Stampfer MJ, Rosner BA, Schernhammer ES. Personal use of permanent hair dyes and cancer risk and mortality in US women: prospective cohort study. BMJ. 2020 Sep 2;370:m2942. doi: 10.1136/bmj.m2942.

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